The Opportunities for Advantage Series of posts will continue this year. Designed to explore how exponential disruption and innovation require organizations to focus efforts to gain advantage, in a recent review of the series we found that there were patterns and groupings which deserved to be highlighted. To start: the opportunities for advantage created by the exponential disruption of the industrial base (including the defense industrial base) coupled with exponential biotechnology innovation to build the bioeconomy of the future. The following is a primer on the potential of such an effort  – including the challenges, threats, risks, and opportunities ahead for your organization in this technology and business ecosystem of the future.