Exponential Organizations’ (ExOs), platforms, ecosystems, and sources of new value creation are based on the disintermediation (innovation that undermines established or incumbent structures) of a market, organization, or industry sector. A strategic suggestion to organizations if they are experiencing disintermediation is to aggressively self-cannibalize, with ecosystems and platforms as the new value creation and capture architectures of a new business model (or – to start – a standalone, but scalable business unit). Is the United States government, specifically the Department of Defense (DoD), experiencing disintermediation? And, if so, is it prepared for the future of exponential innovation?